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自主研发治疗红斑狼疮候选新药,预计将于今年下半年申请上市

来源:科技日报 时间:2019-07-16 16:10:17

科技日报讯 (记者付丽丽)国家“重大新药创制”科技重大专项课题研发团队12日对外公布Ⅱb临床试验数据,宣布治疗系统性免疫疾病的候选新药——RC18(泰它西普)的关键临床研究阶段工作已顺利结束,预计将于今年下半年申请上市。

本临床试验负责人、北京协和医院风湿科主任张奉春表示,泰它西普是靶向BLyS和APRIL的双靶向生物新药,本次研究达到主要临床终点,且主要临床指标与现有药物相比有大幅提高,是治疗系统性红斑狼疮的一个重大突破,具有非常重要的意义。

本次发布的泰它西普是荣昌生物自主研发的国家生物Ⅰ类新药,主要用于治疗系统性红斑狼疮、类风湿性关节炎等自身免疫疾病。目前该药所取得的临床数据在全球在研的治疗系统性红斑狼疮药物中最为突出,具有全球知识产权的“新靶点、新结构、新机制”特征。

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